Effect of Lysergic Acid Diethylamide on Escherichia coli, Strain B/r(lambda)
Abstract
The effect of LSD on E. coli was examined as a test system for damage to genetic material. LSD had a dose-dependent effect on bacterial growth rate. This effect was not amplified by the DNA-repair inhibitor caffeine. The lowering of the growth rate by LSD was shown to be completely reversible upon dilution. LSD was shown to cause a dose dependent extension of the growth recovery lag due to UV damage. Caffeine caused a much larger extension of this lag time.
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 01, 1970
- Accession Number
- AD0701170
Entities
People
- Jack S. Wolpert
- Michael J. Dowler