CS IN WATER: EFFECTS ON HUMAN EYES
Abstract
This was a study of the effects of 0.1% and 0.25% o-chlorobenzylidene malononitrile (CS) in water with 0.5% polysorbate 20 when placed in the human eye. Each of the 16 subjects received one drop or a brief spray in one eye. They could not open their eyes for 10 to 67 seconds, and only after 35 to 135 seconds were they able to read 20/20 letters. The visual incapacitation appeared to be similar for both concentrations. Fluorescein staining of the cornea was assessed under ultraviolet light and with a slitlamp biomicroscope. It was concluded that concentrations of 0.1% and 0.25% CS in water with 0.5% polysorbate 20 that reach the eye in either a drop or a brief spray cause transient conjunctivitis but no corneal damage in man.
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 01, 1969
- Accession Number
- AD0702880
Entities
People
- Millard M. Mershon
- Roy H. Rengstorff