MODE OF FISSION OF BENZENE NUCLEUS IN THE MICRO-ORGANISMS AND REGULATION OF CELL GROWTH AND DIVISION BY BENZENE DERIVATIVES.

Abstract

A species of Flavobacterium is capable of utilizing either D-trytophan or L-tryptophan as the sole source of carbon and energy for aerobic growth. D-Tryptophan is oxidized to indolepyruvic acid and this reaction is followed by a transamination reaction with the eventual formation of L-tryptophan. The organism oxidatively degrades L-tryptophan via L-kynurenine and anthranilic acid. A number of L-amino acids will serve as a source of an amino group for the transamination reaction although L-glutamic acid and L-aspartic acid appear to be the most efficient donors. Glutamine will also function as an amino donor in this microbial system. The conversion D-tryptophan to L-tryptophan in a cell-free system can be demonstrated when an electron acceptor, such as phenazine methosulfate, is present. (Author)

Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1970
Accession Number
AD0703646

Entities

People

  • Norman D. Durham

Organizations

  • Oklahoma State University–Stillwater

Tags

Communities of Interest

  • Energy and Power Technologies

DTIC Thesaurus Topics

  • Amino Acids
  • Anthranilic Acid
  • Aspartic Acid
  • Cell-Free System
  • Cells
  • Electron Acceptors
  • Glutamic Acid
  • Glutamine
  • Kynurenine
  • Tryptophan

Fields of Study

  • Biology

Readers

  • Analytical Chemistry
  • Circadian Sleep-Wake Regulation and Chronobiology

Technology Areas

  • Biotechnology
  • Biotechnology - Bioremediation
  • Biotechnology - Cancer Biotech
  • Microelectronics