RESPONSES OF SKELETAL MUSCLE pH TO INJURY: A NEW TECHNIQUE FOR DETERMINATION OF TISSUE VIABILITY

Abstract

Conventional criteria for estimation of viability of skeletal muscle include direct observation of color, consistency, contractility, bleeding, and the use of various staining methods. The latter techniques have definite limitations which render them impractical or imprecise for clinical application. The present study was designed to evaluate the technique of electrometric surface pH measurement in assessment of skeletal muscle viability following crush, thermal, and high velocity missile injury. Surface electrometric pH of skeletal muscle demonstrates significant changes after crush, thermal, and high velocity missile injury. The anatomic correlation of these changes with the distribution of vital dye indicates that surface hydrogen ion activity of skeletal muscle is readily altered by changes in tissue perfusion. Further studies will be directed toward definition of the extent of pH change which is consistently associated with tissue death.

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Document Details

Document Type
Technical Report
Publication Date
Mar 01, 1970
Accession Number
AD0704451

Entities

People

  • Gene V. Aaby
  • Irwin R. Berman
  • Michael D. Lemieux

Organizations

  • Walter Reed Army Institute of Research

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Biological Staining And Labeling
  • Blood Flow
  • Burns
  • Debridement
  • Infusions
  • Ions
  • Laboratory Animals
  • Lactic Acid
  • Measurement
  • Metabolism
  • Muscles
  • New York
  • Patents
  • Perfusion
  • Protons
  • Skeletal Muscle
  • Tissues

Readers

  • Cardiovascular Physiology
  • Neuroscience
  • Systems Analysis and Design