THE EFFECT OF INTERMITTENT EXPOSURE TO 3% CO2 ON RESPIRATION
Abstract
One healthy male subject was exposed for six days, 15 hours daily, to a CO2 concentration rising from 0 - 3% CO2 at normal oxygen concentrations of 20 - 21% O2. Average data of physiological measurements made (A) prior ot and (B) at the end of the 15-hour exposure to CO2 concentration, rising linearly from 0 - 3% CO2 were pACO2(A): 40.7 mm Hg; pACO2(B): 42 mm Hg; pAO2(A): 100.7 mm Hg; PAO2(B): 114.8 mm Hg; VE(A): 6.28 L/m; VE(B): 12.09 L/m. pACO2 determined at the end of the none-hour air breathing rose from the third day on to reach, at the fifth day, a peak higher than the corresponding value following 15 hours of CO2 inhalation. During the sixth day of intermittent exposure to CO2, pAO2 on air returned to control values. This finding indicates that after three days the nine-hour period of air breathing was insufficient to eliminate the CO2 accumulated during the 15-hour period of CO2 breathing. Ventilatory response to 5% CO2 was increased during intermittent exposure to CO2 and the slope of the CO2 tolerance curve was also increased.
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 13, 1970
- Accession Number
- AD0708030
Entities
People
- C. R. Carey
- J. H. Dougherty Jr.
- Karl E. Schaefer
Organizations
- Naval Submarine Medical Research Laboratory