CROSS INFECTION WITH EIGHTEEN PATHOGENS AMONG CAGED LABORATORY ANIMALS
Abstract
The extent of cross infection among caged laboratory monkeys, guinea pigs, mice, and chickens was examined with 18 pathogens. Experiments were designed to determine if cross infection would be eliminated by (1) ventilated cages, (2) various air-washing procedures, (3) elimination of excreta from cages, (4) ultraviolet irradiation, and/or (5) high efficiency air filters covering the cages. Animals exposed to an aerosol create a hazard to the experiment and experimenter because the usual post-exposure air-washing techniques do not remove microorganisms entrained on the fur. A forceful air-jet ruffling technique greatly reduced microorganisms from the fur. Ultraviolet irradiation or high efficiency air filters on the cages prevented infection of normal animals in adjacent cages. With most microorganisms, animals inoculated other than by aerosol challenge do not show cross infection.
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 16, 1970
- Accession Number
- AD0708651
Entities
People
- Arnold G. Wedum
- Richard H. Kruse