CULTIVATION OF VIRUSES IN A SUSPENSION OF TRANSFERABLE CELLS (Kultivirovanie Virusov v Suspenzii Perevivaemykh Kletok),
Abstract
Deep medium cultures have the capacity of yielding readily and rapidly significant quantities of cells, which means that one can count on obtaining rather large quantities of concentrated viral preparations. By maintaining infected cells in suspension it is possible to obtain a virus -- cell system in which their interaction takes place under homogeneous and controlled conditions, and to pick out a practically unlimited number of identical samples and consequently to make a strict study of the dynamics of processes. To some extent, suspended cultures eliminate the gradient between the acting chemical and the cell, which is inherent in tests using monolayer cultures. It may be asserted that in practice the method of suspension cultivation of viruses, which has a number of important advantages, reproduces all of the advantages of cultivation of monolayer cells. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 14, 1970
- Accession Number
- AD0708788
Entities
People
- A. S. Novokhatskii
Organizations
- United States Army Foreign Science and Technology Center