EFFECTS OF AN ORGANOPHOSPHORUS PESTICIDE ON REPRODUCTION IN THE RAT

Abstract

The toxic effects of organophosphorus insecticides are commonly ascribed to cholinesterase (CHE) inhibition. A search of the scientific literature revealed the well-established fact that a number of chlorinated pesticides adversely affect reproduction in mice and rats. However, little is known about the effects of organophosphorus pesticides on reproduction. Disulfoton was selected for this study because it is a widely used organophosphorus insecticide for which the acutely toxic, nonlethal dose in rats has been established.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1970
Accession Number
AD0709327

Entities

People

  • Boyd R. Endecott
  • Gerald D. Hanneman
  • Leonard C. Ryan
  • Paul W. Smith

Organizations

  • Federal Aviation Administration

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Animals
  • Aviation Medicine
  • Chemical Synthesis
  • Chemistry
  • Enzyme Inhibitors
  • Inhibition
  • Insecticides
  • Laboratory Animals
  • Literature
  • Materials
  • New York
  • Organic Phosphorus Compounds
  • Pesticides
  • Phosphorus Compounds
  • Pregnancy
  • Scientific Literature

Fields of Study

  • Agricultural and Food sciences

Readers

  • Aquatic Ecology
  • Neurotoxicology
  • Theoretical Analysis.