THE TOXICITY AND THE NATURE OF THE ACTION OF FLUORINATED ALCOHOLS (TRIFLUOROETHANOL AND 1,1-DIHYDROPERFLUOROBUTANOL)

Abstract

The paper discusses the toxic action of fluorated alcohols (trifluoroethanol and 1,1-dihydroperfluorobutanol) and different routes of their access into the organism of experimental animals. The fluorated alcohols under study are shown to be toxic compounds. Topical irritating action at the site of their application and general toxic effect of these poisons, characterized by manifestations of their narcotic action on the central nervous system and by dystrophic changes in parenchymatous organs, were revealed. Maximum permissible concentrations of their fumes in the air of industrial premises have been established, which for trifluoroethanol is 10 mg/cu m and for 1,1- dihydroperfluorobutanol - 20 mg/cum.

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Document Details

Document Type
Technical Report
Publication Date
May 28, 1970
Accession Number
AD0710292

Entities

People

  • M. S. Tolgskaya
  • T. K. Nikitenko

Tags

DTIC Thesaurus Topics

  • Air Force
  • Animals
  • Body Weight
  • Cells
  • Central Nervous System
  • Corneal Diseases
  • Diseases And Disorders
  • Foreign Technology
  • Hippuric Acid
  • Intoxication
  • Laboratory Animals
  • Nervous System
  • Neurons
  • Occupational Diseases
  • Poisoning
  • Rodents
  • Toxicity

Readers

  • Organic Chemistry
  • Toxicology/Environmental Toxicology