Permeability of the Skin to Gases

Abstract

The report presents a study of the permeability of human skin (epidermis and stratum corneum) to vapors and gases. Physical measurements include the determination of the solubility of homologous series of organic vapors, alkanes, alcohols, etc. ... in stratum corneum; the permeability of these substances through epidermis and the measurement of gas-tissue sorption rates and equilibria. Primary emphasis is placed upon the measurement of fundamental physical constants characteristic of the tissue and relevant to diffusion. The effect of hydration of the permeability of gases and vapors is studied. The mechanism of diffusion of gases through dry stratum corneum is discussed and compared with diffusion through hydrated tissue.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 1970
Accession Number
AD0713865

Entities

People

  • Robert J. Scheuplein

Organizations

  • Massachusetts General Hospital

Tags

Communities of Interest

  • Biomedical
  • C4I
  • Ground and Sea Platforms

DTIC Thesaurus Topics

  • Alcohols
  • Alkanes
  • Biological Sciences
  • Classification
  • Contracts
  • Crystal Oscillators
  • Desorption
  • Diffusion
  • Diffusion Coefficient
  • Epidermis
  • Equations
  • Hydration
  • Measurement
  • Skin
  • Sorption
  • Tissues
  • Vapor Pressure

Readers

  • Electrochemical Engineering/ Fuel Cell Technologies
  • Groundwater Contamination Remediation.
  • Plasma Physics.