Hemoglobin Function in Stored Blood. IV. Red Cell Viability and Function in ACD and CPD with Adenine and Inosine.
Abstract
The importance of adenine for maintaining ATP and thus shelf life of stored blood has been reaffirmed. Studies reported here indicate that 0.25 mM adenine, or one-half the amount previously specified, may be sufficient to provide a 5-week shelf life. The initial concentration of adenine can be reduced further--to 0.125 mM, if 10 mM inosine and 0.125 mM adenine are added at 2 weeks. This use of inosine with small concentrations of adenine provides for near normal hemoglobin function as well as red cell viability during the 5-week storage period. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 30, 1970
- Accession Number
- AD0714186
Entities
People
- Mildred C. Edinger
- Roy B. Dawson Jr.
- Thomas J. Ellis
Organizations
- United States Army Medical Research Laboratory