Studies on Stored Liquid Whole Blood. IV. Effects of Temperature and Mechanical Agitation.
Abstract
Banked blood maintained at 4 C was compared with blood stored at 10C and 22C, with and without simple physical stress. Little change in certain chemical tests was detected except in those units stored at 22C. These changes were increased if agitation was involved and were apparent to a greater degree in stored units from which the plasma had been removed. The changes began to exceed those found in the controls when blood was stored beyond 21 days, and were significantly different after 28 days. Blood warmed to 22C for 24 hours manifested changes in chemical levels and in the in vivo posttransfusion survival, but the values were not significantly different until blood had been stored at least 28 days. The findings suggest that the ability of banked blood to withstand temperature and physical stress decreases with length of storage. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 24, 1970
- Accession Number
- AD0714188
Entities
People
- Charles E. Shields
Organizations
- United States Army Medical Research Laboratory