Neurotropic Effects in Relation to Chemical Structure.

Abstract

Attempts were made to prepare both the endo and exo isomers of V. 1,4-dihydro-9, 10-dimethyl-1,4-ethanonaphthalene-2,3-dicarboxylic anhydride. Evidence for the isolation of a eutectic mixture of both is presented. A continuation of the syntheses and biological evaluations of substituted 11-aminomethyl-9,10-ethano-9,10-dihydro-anthracenes is also reported. The synthese of intermediates of a new series of dihydroanthracenes possessing a two-carbon side chain, 11-(alpha-hydroxy-beta-aminoethyl) -9,10-dihydroanthracene, are contained in this report. Continuation of the syntheses of the hydrochloride and methiodide salts of three series of 1-dialkylaminoacetyl-3-keto-1,2,3,4,-tetrahydroquinoxalines is also presented. (Author)

Document Details

Document Type
Technical Report
Publication Date
Aug 31, 1965
Accession Number
AD0715386

Entities

People

  • Hugh B. Donahoe
  • William J. Hufker

Organizations

  • Saint Louis University

Tags

DTIC Thesaurus Topics

  • Anhydrides
  • Aromatic Polycyclic Hydrocarbons
  • Chemical Compounds
  • Organic Compounds
  • Test And Evaluation

Fields of Study

  • Chemistry

Readers

  • Organic Chemistry