Neurotropic Effects in Relation to Chemical Structure.

Abstract

The exo isomer of 1,4-dihydro-9,10-dimethyl-1,4-ethanonophthalen-2,3-dicarboxylic anhydride was isolated and characterized. Biologically testable derivatives were also prepared. Two series of 11-(omega-dialkylaminoalkyl)-9,10-ethano-9,10-dihydroanthracenes were synthesized and selected compounds were biologically screened. Three series of amino esters and amino amides derived from 9,10-ethano-9,10-dihydroanthracene derivatives were also reported. New types of bi-planar compounds having a phenolic diphenylmethane structure were prepared. Their analgesic activity was also determined. (Author)

Document Details

Document Type
Technical Report
Publication Date
May 31, 1966
Accession Number
AD0715389

Entities

People

  • Hugh B. Donahoe
  • William J. Hufker

Organizations

  • Saint Louis University

Tags

DTIC Thesaurus Topics

  • Anhydrides
  • Chemical Compounds

Fields of Study

  • Chemistry

Readers

  • Organic Chemistry