An Investigation of Bonding Mechanisms at the Interface of a Prosthetic Material.
Abstract
The two primary objectives of this program are: (1) to achieve a direct chemical bond between orthopaedic devices and bone using glass and glass-ceramic materials or coatings, and (2) to develop a scientific understanding of the interfacial reactions occurring between materials and bone. The report summarizes evidence developed in this laboratory of direct chemical bonding between glass-ceramic implants and rat femurs. A comparison of morphologic techniques developed for the evaluation of the bone-ceramic interface is presented. In-vitro studies of hydroxyapatite crystallization on glass-ceramics have shown bonding of the bone mineral to the implant material. The kinetics of interfacial solubility and pH changes of the implants have also been measured. A preliminary histo-physio-chemical model for the interfacial reactions leading to direct chemical bonding is advanced based on in-vitro and in-vivo studies. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 01, 1970
- Accession Number
- AD0715732
Entities
People
- L. L. Hench
- T. K. Greenlee
- W. C. Allen
Organizations
- University of Florida