Steroid Hormones in the Preservation of Human Blood.

Abstract

Progesterone is effective in protecting erythrocytes during storage by minimizing spontaneous lysis, changes in osmotic resistance and loss of ATP. The greatest effect is obtained by addition of progesterone plus adenine to erythrocytes suspended in phosphate buffer. Testosterone and androsterone are without effect. The use of the 'osmotic fragility index' to represent the osmotic resistance of erythrocytes is proposed. (Author)

Document Details

Document Type
Technical Report
Publication Date
Nov 09, 1970
Accession Number
AD0715749

Entities

People

  • Frankc DeVenuto
  • Sarah M. Wilson

Organizations

  • United States Army Medical Research Laboratory

Tags

DTIC Thesaurus Topics

  • Biomolecules
  • Blood
  • Chemical Compounds
  • Erythrocytes
  • Fragility
  • Hormones
  • Hormones Hormone Substitutes And Hormone Antagonists
  • Progesterone
  • Resistance
  • Sex Hormones
  • Testosterone

Fields of Study

  • Biology

Readers

  • Cardiovascular Physiology
  • Molecular and Cellular Biochemistry
  • Strategic Security Studies