Mode of Radiation Resistance of Clostridium Botulinum Spores
Abstract
Work was conducted to delineate the mechanisms responsible for the extraordinary resistance of Clostridium botulinum spores to ionizing radiation as compared with vegetative cells. The findings indicate that the progression from the high resistance of spores to the sensitivity of vegetative cells proceeds in at least three discrete steps. Several biochemical events have been shown not to play a key role in the resistance and the state of hydration and configuration of DNA has emerged as a prime candidate to explain the changes in resistance.
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 01, 1970
- Accession Number
- AD0717563
Entities
People
- Brooks D. Church
- Durwood B. Rowley
- Gregory R. Germaine