Multiplication and Antibody Formation of Japanese Encephalitis Virus in Snakes
Abstract
In studies designed to investigate the role of snakes in the ecology of Japanese encephalitis (JE) virus in Korea, 747 snakes representing 4 different species were collected during 1966 and 1967. Two strains of JE virus were isolated from the snakes, E. rufodorsata CANTOR caught in the rural area near Seoul. Plasma samples from 1,775 snakes collected in Korea during 1965 and 1969 were assayed for serologic evidence of infection with JE virus by hemagglutination inhibition test. Hemagglutination inhibiting antibodies were demonstrated in 54% of the snakes. Plasma samples from 683 snakes collected during 1968 and 1969 were assayed for serologic evidence of JE infection by an in vitro plaque-neutralization method. Neutralizing antibodies were demonstrated in 2.8% of total snakes. That snakes are effective as reservoir hosts for JE virus is discussed.
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 01, 1970
- Accession Number
- AD0721622
Entities
People
- Ho Wai Howard Lee
Organizations
- Seoul National University