The Oral Toxicity of Hexavalent Chromium

Abstract

The object of this investigation was to determine the effect on albino rats of the oral ingestion of water containing hexavalent chromium. The test animals drank concentrations of hexavalent chromium as high as 200 mg./1. as potassium dichromate equivalent to 25 mg. of chromium per kilogram of body weight, over a period of 33 days, without ill effects definitely attributable to the chromium. The presence of chromium in the drinking water reduced the water consumption of the rats. The average consumption of water containing 200 mg. chromium per liter was 27% less than the consumption of tap water.

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Document Details

Document Type
Technical Report
Publication Date
Mar 19, 1947
Accession Number
AD0722266

Entities

People

  • C. D. Gates
  • J. M. Sanchis
  • Lucile B. Pack

Tags

DTIC Thesaurus Topics

  • Animals
  • Biomedical Research
  • Body Weight
  • Chemistry
  • Chromium
  • Chromium Compounds
  • Digestive System Processes
  • Drinking Water
  • Elements
  • Gas Masks
  • Group 6 Elements
  • Health Services
  • Laboratory Animals
  • Medical Laboratories
  • Metals
  • Potassium
  • Potassium Dichromate

Readers

  • Environmental Engineering
  • Surface Engineering/Surface Coating Technology.
  • Toxicology/Environmental Toxicology