The Effect of Intermittent Exposure to 3% CO2 on Acid-Base Balance and Electrolyte Excretion
Abstract
The effects of intermittent exposure to CO2 on acid-base balance was investigated. One subject was exposed for six days to increasing CO2 rising at a constant rate from 0.03 to 3.0% CO2 within a period of 15 hours followed by a nine hour period of air breathing. To assess the acid-base parameters 'arterialized' capillary blood was taken from the finger twice daily at 8 AM and 11 PM corresponding with the beginning and end of the intermittent exposure to CO2. Urine specimans were collected at the same times daily while venous blood samples were obtained on alternate days. Hydrogen ion concentrations and PCO2 in the arterialized capillary blood were found increased during the air breathing periods of the fourth and fifth day but returned to normal during the sixth day. The elimination of this CO2 accumulation in the blood was accomplished through renal mechanism showing a marked increase in urine volume, organic acids, titratable acidity, ammonia and hydrogen ion excretion during the fourth and fifth day. The stress effect produced by intermittent exposure to CO2 in this subject must have been minimal since the 17-hydroxysteroid excretion did not change.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 16, 1970
- Accession Number
- AD0722662
Entities
People
- Arthur A. Messier
- C. C. Morgan
- Karl E. Schaefer
- Michael J. Jacey
Organizations
- Naval Submarine Medical Research Laboratory