Acute Toxicity of Carbon Monoxide Under Hyperbaric Conditions

Abstract

The toxicity of carbon monoxide was evaluated under conditions of elevated pressure to determine if a pressurized environment would result in an altered response of an animal to the gas. The results indicate that the toxicity of carbon monoxide is not altered by increases in ambient pressure up to approximately 8 ATA provided the partial pressure of oxygen in the atmosphere remains constant. Carbon monoxide, however, is unique in its mode of action and no attempts were made to evaluate any subjective effects, chronic effects, behavioral effects or measurements of decrements in performance during the exposures. Therefore, one should not generalize from data on carbon monoxide as to the toxicity of other materials under hyperbaric conditions.

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Document Details

Document Type
Technical Report
Publication Date
Dec 01, 1970
Accession Number
AD0727508

Entities

People

  • Charles S. Rose

Organizations

  • Air Force Research Laboratory

Tags

DTIC Thesaurus Topics

  • Animals
  • Barometric Pressure
  • Carbon Monoxide
  • Chambers
  • Chemistry
  • Dielectric Gases
  • Ecotoxicology
  • Gases
  • Hyperbaric Chambers
  • Hyperbaric Conditions
  • Hypobaric Conditions
  • Materials
  • Measurement
  • Partial Pressure
  • Pressure Gages
  • Rodents
  • Toxicology

Fields of Study

  • Environmental science

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