Gas Chromatographic Retention Data,

Abstract

Gas chromatography (GC) is one of the more useful instrumental methods of analysis in biochemical research for toxicology and pollution studies. This paper discusses an approach to the solution of the problem of reproducibility of retention data. The main purpose is to present a method of reporting gas chromatographic data that is reproducible, meaningful and relatively easy to generate. In addition, two questions will be discussed: (1) What is retention data and (2) What value does it have for the toxicologist. The application of the Kovats Retention Index System to toxicology is discussed. The system relies on the basic approach of analytical chemistry of bracketing an unknown with two standards. The Kovats system has the advantage that it can describe on its scale any compound that can be chromatographed. This general index system recommends itself for use in the expression of retention data in toxicological studies.

Document Details

Document Type
Technical Report
Publication Date
Dec 01, 1970
Accession Number
AD0727523

Entities

People

  • Anthony A. Thomas
  • Sheldon A. London
  • William H. Toliver Sr.

Organizations

  • Air Force Research Laboratory

Tags

DTIC Thesaurus Topics

  • Analytical Chemistry
  • Analytical Chemistry Techniques
  • Biological Sciences
  • Chemistry
  • Chromatography
  • Ecotoxicology
  • Gas Chromatography
  • Pharmacology
  • Reproducibility
  • Standards
  • Toxicology

Fields of Study

  • Chemistry

Readers

  • Analytical Chemistry
  • Systems Analysis and Design