Acute Toxicity of Oxygen Difluoride
Abstract
Because of the potential use of oxygen difluoride (OF2) being used as an oxidizing fuel in the missile industry, it became necessary to define and characterize the hazards associated with the handling of this compound. The assessment of OF2 toxicity in this study was made by exposing four species of animals (monkeys, dogs, rats and mice) to various concentrations of the gas for 15 and 60 minutes. The acute effects of OF2 inhalation were shown mainly to be respiratory in nature. Tachypnea was the most prominent toxic sign observed in rodents. Upper respiratory and gastrointestinal tract irritations were observed in dogs and monkeys. The mortality response demonstrated a significant difference in the susceptibility of the various species to the toxic effects of the gas. Rats and mice were found to be much more susceptible than monkeys or dogs.
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 01, 1970
- Accession Number
- AD0727525
Entities
People
- Harvey V. Davis
Organizations
- Air Force Research Laboratory