Studies of the Effect of Personality on Reactivity to LSD

Abstract

Case records of 52 Army volunteers given from 1.1 to 2.0 micrograms/ kg of LSD orally between 1962 and 1966 were studied. Since 1966 no further studies have been performed. Significant relationships were found between personality (as measured by the Minnesota Multiphasic Personality Inventory and Army General Intelligence Test) and performance following administration of LSD. Resistant subjects at lower doses were found to be more intelligent, energetic, and outgoing. Sensitive subjects were less intelligent, constricted, more anxious, over-controlled, and dependent. At the higher doses the picture was not as clear, but personality factors were still highly correlated with performance. The Pa (paranoia) scale had a higher correlation with performance than did dose. The K (positive test-taking attitude), Hs (hypochondriasis), and Si (social introversion) scales were positively correlated with performance at lower doses and negatively correlated with performance at higher doses.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 1971
Accession Number
AD0728449

Entities

People

  • Jack A. Klapper
  • James S. Ketchum
  • Kragg P. Kysor
  • Michael A. Mccolloch
  • Van M. Sim

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Army Personnel
  • Biomedical Research
  • Drug Abuse
  • Drug Resistance
  • Health Services
  • Incapacitating Agents
  • Intelligence Tests
  • Lysergic Acids
  • Maryland
  • Medical Personnel
  • Minnesota
  • New York
  • Pain
  • Personality
  • Psychiatry
  • Psychology
  • United States

Fields of Study

  • Psychology

Readers

  • Educational Psychology
  • Psychometric Testing or Psychological Assessment.
  • Toxicology/Environmental Toxicology