A Comparison of the Response of Canine and Primate Species to Bacterial and Bacterial Endotoxin
Abstract
The major purpose of this report is to review findings from our laboratory comparing the actions of intravenously administered live E. coli organisms and E. coli endotoxin in dogs and monkeys. The preponderance of data obtained from such experiments seems to indicate that the endotoxin shock model is a valid means of eliciting many of the characterisitcs of shock seen in the patient. Differences are apparent between the models, however, and further research is therefore needed to perfect a more adequate experimental preparation.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 28, 1971
- Accession Number
- AD0728789
Entities
People
- Lerner B. Hinshaw
Organizations
- University of Oklahoma