Peripheral and Cardiac Factors in Experimental Septic Shock

Abstract

Peripheral pooling mechanisms apparently predominate in the early phase of endotoxin shock in bringing about a decrease in cardiac output. Left ventricular function appears to be entirely normal and only a longer sustained period of hypotension would be expected to bring about impairment of myocardial performance. A variety of indirect mechanisms resulting from poor systemic hemodynamic status may ultimately contribute to myocardial failure in the later stages of shock.

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Document Details

Document Type
Technical Report
Publication Date
Aug 30, 1971
Accession Number
AD0728791

Entities

People

  • Lerner B. Hinshaw

Organizations

  • University of Oklahoma

Tags

DTIC Thesaurus Topics

  • Blood
  • Blood Flow
  • Cardiovascular Physiological Phenomena
  • Cardiovascular Physiological Processes
  • Cardiovascular System
  • Contracts
  • Diseases And Disorders
  • Endotoxins
  • Escherichia Coli
  • Heart
  • Heart Failure
  • Hemorrhagic Shock
  • Hypotension
  • Military Research
  • Oklahoma
  • United States
  • Universities

Fields of Study

  • Biology
  • Medicine

Readers

  • Cardiovascular Physiology
  • Economics