Pathological Response of the Lung to Certain Inhaled Irritants

Abstract

Acute exudative or hemorrhagic lesions were seen in the lungs of monkeys, dogs, rats and mice exposed to high concentrations of ozone, nitrogen dioxide and oxygen, while subacute proliferative pulmonary lesions were best demonstrated in monkeys exposed to high concentrations of oxygen and surviving the early exudative phase of the toxic response. The chronic granulomatous response was best illustrated in the lungs of dogs exposed to beryllium- containing dusts and allowed to recover for 30-36 months.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1967
Accession Number
AD0728859

Entities

People

  • Farrel R. Robinson

Organizations

  • Air Force Research Laboratory

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Air Force
  • Biomedical Research
  • Blood
  • Cells
  • Connective Tissue
  • Endothelial Cells
  • Environment
  • Environmental Pollutants
  • Hemorrhage
  • Irritants
  • Lung Diseases
  • Medical Personnel
  • Nitrogen Oxides
  • Tissues
  • Toxicity
  • Toxicology
  • Universities

Fields of Study

  • Medicine

Readers

  • Combustion science or combustion engineering.
  • Toxicology/Environmental Toxicology