Analysis of Biosynthesis of Nucleic Acids and Several Enzyme Activities in the Progression of Japanese Encephalitis Virus Infection of Cells of the Central Nervous System.
Abstract
The multiplication of Japanese encephalitis virus (JEV) inoculated intracerebrally in the mouse was examined in its hippocampus neurons under application of high energy electron microscopy and cytochemical analysis of several enzymes and chemical components. High voltage electron microscopy has made it possible to observe the three-dimensional structure of cellular elements appearing in the viral factory where viral particles are developed. Autoradiography has confirmed that nucleic acid is synthesized in mitochondria in the infected neutrons. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 01, 1971
- Accession Number
- AD0730763
Entities
People
- Gonpachiro Yasuzumi
Organizations
- Nara Medical University