Sickledex Test for S Hemoglobin: A Critique.
Abstract
When the reagents, reactions, and principles of the Sickledex test are understood in terms of modern molecular biology, it is believed that the Sickledex test can be an invaluable and productive tool in the discovery not only of hemoglobin S but other hemoglobinopathies as well, provided: (1) certain pitfalls of false positive and false negative reactions are recognized; (2) urea is used to modify the test; and (3) all positive Sickledex specimens are subsequently studied by hemoglobin electrophoresis technique. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 04, 1971
- Accession Number
- AD0732354
Entities
People
- Frank R. Camp Jr.
- Jeanne M. Lusher
- Nicholas F. Conte
- Raymond L. Henry
- Robert M. Nalbandian
Organizations
- United States Army Medical Research Laboratory