Hyperbaric Air and Corneal Vascularization
Abstract
Hypoxia is one of the factors postulated as promoting vascularization of the cornea. However, previous experiments designed to increase tissue oxygen for short or intermittent periods have had no effect in retarding neovascularization. The present study utilized rabbit exposure to hyperbaric air for continuous periods of up to two weeks to increase tissue oxygen, and demonstrated no effect on the neovascularization caused by sodium hydroxide burns of the cornea. This confirms previous experimental results and tends to rule out inadequate time periods or intermittency of exposure as factors in previous negative results.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 24, 1971
- Accession Number
- AD0732398
Entities
People
- Donald W. Klopp
- Robert J. Kaiser
Organizations
- Naval Submarine Medical Research Laboratory