An Animal Model for Acute Respiratory Failure.
Abstract
Adult baboons with their respiration moderately impeded go into respiratory failure without evident impairment of the gas-exchange properties of the lung and without significant alteration in their pulmonary mechanics. No sizeable increases in oxygen consumption occurred when impeded breathing was imposed on the animals, although increased elastic work was the costliest in terms of oxygen consumption. This points to a local limitation in performance or metabolism of the respiratory muscles rather than competition of the muscles with other tissues for a limited oxygen supply. The limitation is not in the capacity of the respiratory machinery to exchange more gas at a reasonable oxygen cost. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 1971
- Accession Number
- AD0732438
Entities
People
- H. J. Proctor
- L. D. Homer
Organizations
- Brown University