Thermal Inactivation of Viruses. Report 1. The Relationship between the Rate of Inactivation and Temperature
Abstract
The speed and dynamics of the inactivation of virus at various temperatures depends on multiple factors. Basic among them are the nature and structure of the viruses, their genetic pecularities, the state of the medium in which the viral molecules are suspended, and the period and conditions of the preservation of viral preparations. Some principles of the inactivation of RNA- containing viruses under various conditions were determined using Venezuelan Equine Encephalomyelitis (VEE), Sindbis (SV), and Vesicular Stomatitis (VSV) viruses. By basic functional tests the dynamics of change in infective activity of viruses were studied. The report gives an account of the results of investigating the constants of the rate of inactivation at various temperatures, as well as data on some thermodynamic characteristics describing the process of loss of infective activity by viruses.
Document Details
- Document Type
- Technical Report
- Publication Date
- Nov 18, 1971
- Accession Number
- AD0732710
Entities
People
- A. S. Novokhatskii