A Concentration-Dependent Attenuation of Toxic Oxygen Effects in the Mouse.
Abstract
Ninety male albino mice were exposed to 4, 6, or 8 atm oxygen partial pressure in 100%, 50%, or 25% dilutions. Tolerance was measured in terms of times to convulsion and times to death. Results indicated (a) both convulsion times and death times tended to increase with decreases in concentration, (b) the degree of change in tolerance as a function of concentration was greater for the low partial pressures, and (c) convulsion times and death times showed significant correlation only in the 4 atm partial pressure condition. The results further indicate a distinct decrease in susceptibility to toxic oxygen effects with increases in absolute pressure at fixed pO2. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 15, 1971
- Accession Number
- AD0733418
Entities
People
- Jerry D. Burns
Organizations
- Arizona State University