Blood Cholinesterase Variation in Sheep under Different Holding Conditions.
Abstract
A monitoring program, including the use of domestic sheep as sentries for open-air tests of anticholinesterase agents, was developed in the event emergency circumstances would dictate that this testing program be resumed. The sheep would be placed in monitor pens on the periphery of the test grid after each test, and blood cholinesterase (ChE) activity would be measured periodically. This report presents a method for measuring ChE in erythrocytes and plasma of sheep and describes a baseline study in which sheep selected as indicator animals were placed in monitor baseline study in which sheep selected as indicator animals were placed in monitor pens to evaluate their physiological responses, especially ChE variations. Significant depressions of erythrocyte and plasma ChE occurred in some animals. These depressions were incorporated into estimates of normal ChE variation for each sentry sheep. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 01, 1971
- Accession Number
- AD0734824
Entities
People
- George D. Edwards