Studies of Fluorometric Assay Procedures for Lysergic Acid Diethylamide

Abstract

Studies of the available fluorometric assay procedures for LSD-25 are described for possible clinical application. Variability of plasma 'blank' background fluorescence values were found to prohibit the use of standard fluorometric procedures without modification. A little known fluorometric procedure is described which minimuzes this problem and maintains the sensitivity of the assay at the nanogram level. Modifications of this method are suggested which could increase the sensitivity of this method to the subnanogram level.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Feb 01, 1972
Accession Number
AD0737671

Entities

People

  • Peter J. Kasvinsky

Organizations

  • United States Army Aeromedical Research Lab

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Acids
  • Blood
  • Blood Plasma
  • Classification
  • Drug Abuse
  • Excitation
  • Extraction
  • Fluorescence
  • Hallucinogens
  • Linearity
  • Lysergic Acids
  • Materials
  • Pharmacology
  • Security
  • Sensitivity

Fields of Study

  • Chemistry

Readers

  • Analytical Chemistry
  • Child and Adolescent Substance Abuse Science in Autism Spectrum Disorders.