Features Peculiar to Nicotinic Acid Metabolism in Acute Respiratory Diseases

Abstract

During sporadic acute respiratory sicknesses, tonsillitis, and pneumonia, stereotypic deviations in the metabolism of nicotinic acid, including decreased level of pyridine nucleotides in whole blood and erythrocytes and in raised spontaneous removal in the urine of N1-methylnicotinamid and its 6-pyridon were observed. Expressivity and duration of metabolic shifts of nicotinic acid is found in direct relation to the intensity and duration of inflamatory changes of the breathing apparatus. To compensate for the losses of nicotinic acid in the acute phase of the disease, addition of the vitamin in the food in a daily dose of 40>80mg, granulated, was ordered.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1972
Accession Number
AD0738285

Entities

People

  • A. S. Ostapenko
  • P. D. Starshov

Tags

DTIC Thesaurus Topics

  • Acids
  • Anti-Bacterial Agents
  • Biochemistry
  • Blood
  • Chemical Synthesis
  • Chemistry
  • Diseases And Disorders
  • Health Services
  • Heterocyclic Acids
  • Infectious Diseases
  • Metabolism
  • Nicotinic Acid
  • Protein Metabolism
  • Proteins
  • Respiratory System
  • Respiratory Tract Diseases
  • Therapy

Fields of Study

  • Biology
  • Medicine

Readers

  • Analytical Chemistry
  • Cardiovascular Physiology
  • Immunology