Studies on the Effect of Shock on Red Cell Surface Charge in Primates
Abstract
Red cell electrophoretic mobilities have been determined on cells from 6 baboons subjected to hemorrhagic shock and 2 baboons in E. coli shock. Studies of cells suspended both in saline and in their own plasma showed electrophoretic mobility in hemorrhagic shock to be unchanged from control values. Power function analysis showed the maximum undetectable change for cells measured in saline would be 6.7%, and in plasma 12.2%. Use of either heparin or EDTA as anticoagulant, or absence of anticoagulant, did not affect the mobilities of either control or shock cells. It is concluded that loss of red cell electronegativity is not an important factor in producing red cell aggregation in hemorrhagic shock, but that this may be of significance in the septic shock.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 1971
- Accession Number
- AD0740984
Entities
People
- D. L. Horwitz
Organizations
- Naval Medical Research Center