A Study of a Possible Method for the Quantitative Non-Destructive Evaluation of Peripheral Nerve Regeneration.
Abstract
The Geoscience's peripheral nerve generation monitoring study consisted of the design and fabrication of nerve action potential electrodes that possess prongs that pierce Schwann and myelin sheaths when attached. In addition, ways of insulating the electrodes from tissues surrounding the nerve were investigated. In vitro nerve action potential experiments were performed with an instrumented rabbit sciatic nerve. Amplitudes and conduction velocities were measured by sensing electrodes as nerve cross sections were progressively severed. The reductions in signal amplitude as the severing process proceeded were studied. Prong type electrodes which pierce the sheaths were used in these experiments and were found to give stable signals that appeared to be independent of external pressures applied to the attachment. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 29, 1972
- Accession Number
- AD0742456
Entities
People
- E. Allred
- G. L. Hody
- H. F. Poppendiek