Effect of Increasing Doses of Ionizing Radiation on Liver Enzymes Involve in Fatty Acid Synthesis

Abstract

The effect of increasing doses of x rays and of mixed neutron-gamma radiation on the fatty acid synthesizing liver enzyme system in rats has been investigated. It was found that the activity of this enzyme system first increased with radiation dose and then decreased in rats exposed to either x rays or mixed neutron-gamma radiation. Acetyl CoA carboxylase activity was found to be more sensitive to mixed neutron-gamma radiation (decreased) than to x rays, whereas fatty acid synthetase appeared to be more sensitive to x rays (increased) than to mixed neutron-gamma radiation.

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Document Details

Document Type
Technical Report
Publication Date
Mar 01, 1972
Accession Number
AD0743062

Entities

People

  • C. G. Mchale
  • George N. Catravas

Organizations

  • Armed Forces Radiobiology Research Institute

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Biological Sciences
  • Biology
  • Fatty Acids
  • Gamma Rays
  • Health Services
  • Ionizing Radiation
  • Military Research
  • Navy
  • New Mexico
  • New York
  • Nuclear Energy
  • Nuclear Medicine
  • Public Health
  • Radiation
  • Radiologic Health
  • Radiology
  • X Rays

Fields of Study

  • Physics

Readers

  • Analytical Chemistry
  • Toxicology/Environmental Toxicology
  • Vector-Borne Disease and Entomology