Drug Absorption: Some Mathematical Considerations

Abstract

Using the absorption equation of Wagner and Nelson and the integrated form of the equation describing the plot of plasma concentration versus time, formulas were derived which may be helpful in comparing rates of drug absorption. The percentage absorbed over a specified time period and the time required for absorption to be 25%, 50%, 75%, or 99% complete can be readily calculated if it is assumed the basic equations are valid.

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Document Details

Document Type
Technical Report
Publication Date
May 01, 1972
Accession Number
AD0743174

Entities

People

  • Frederick R. Sidell

Tags

DTIC Thesaurus Topics

  • Absorption
  • Biological Sciences
  • Biomedical Research
  • Equations
  • Governments
  • Integrals
  • Maryland
  • Pharmaceutical Preparations
  • United States
  • United States Government

Readers

  • Analytical Chemistry
  • Calculus or Mathematical Analysis