Susceptibility of Rodents to Oral Plague Infection: A Mechanism for the Persistence of Plague in Inter-Epidemic Periods

Abstract

Oral infection of rodents with Pasteurella pestis has been demonstrated with both fully virulent and avirulent strains. Sustained rodent plague epizootics have been initiated and maintained in the absence of the classical flea vector. Transmission was due to cannibalism of the dying rodents by their healthy cagemates. Oral infection is considered to provide a plausible mechanism for the persistence of plague in an area where conditions are temporarily unsuitable for flea transmission.

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Document Details

Document Type
Technical Report
Publication Date
Sep 07, 1971
Accession Number
AD0744588

Entities

People

  • D. C. Cavanaugh
  • Daniel N. Harrison
  • James H. Rust Jr.
  • John D. Marshall Jr.

Organizations

  • Walter Reed Army Institute of Research

Tags

DTIC Thesaurus Topics

  • Animals
  • Biological Toxins
  • Diseases And Disorders
  • Immunity
  • Infection
  • Infectious Diseases
  • Laboratory Animals
  • Lethal Dosage
  • Lymph Nodes
  • Lymphatic System
  • Materials
  • Rats
  • Rodents
  • Standards
  • Tissues
  • Wildlife
  • Wound Infections

Fields of Study

  • Biology

Readers

  • Infectious Disease/Epidemiology
  • Microbial Pathology
  • Theoretical Analysis.