Hemoglobin Function in Stored Blood: XII. Effects of Varying Phosphate Concentrations on Red Cell ATP and 2,3-DPG with Adenine and Inosine.
Abstract
Adenine in a concentration of 2 mM was most effective for maintaining 2,3-DPG and ATP levels under the conditions of the study. When the preservative contained adenine and inosine the highest concentrations of phosphate, 6 mM and 8 mM, maintained both ATP and 2.3-DPG better during the first two weeks; however, during the third week the intermediate concentration of phosphate, 4 mM, seemed to be as good or better than all other preservatives for maintaining 2,3-DPG and ATP. After three weeks of storage there appeared to be little difference between preservatives with respect to maintaining 2,3-DPG although ATP was better maintained in both the adenine and the adenine plus inosine preservatives containing high phosphate concentrations. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 30, 1972
- Accession Number
- AD0745112
Entities
People
- R. Ben Dawson Jr.
- Walter F. Kocholaty
Organizations
- United States Army Medical Research Laboratory