Structure of Brain Lipid-Protein Complexes.

Abstract

The effect of direct current voltages on films of brain phospholipids and mixtures of these lipids, cholesterol and cerebroside were examined using infrared-spectral methods. It was found that the bands assigned to the vibrations of the phosphate group and the -(CH2)n- group in long fatty acid chains change intensity with the applied field. Two new proteolipid fractions have been isolated from the treatment of brain tissue with 4M NaCl, 4M PL and R-PL. To obtain useable films of insoluble lipid-protein complexes such as neurokeratin, trypsin-resistant-protein residue, etc., it was found that these complexes were soluble in trifluoracetic acid.

Document Details

Document Type
Technical Report
Publication Date
Jun 01, 1971
Accession Number
AD0745315

Entities

People

  • Leopold May

Organizations

  • The Catholic University of America

Tags

DTIC Thesaurus Topics

  • Biomolecules
  • Chemical Compounds
  • Cholesterol
  • Direct Current
  • Electricity
  • Fatty Acids
  • Intensity
  • Lipids
  • Membrane Lipids
  • Vibration
  • Voltage

Fields of Study

  • Chemistry

Readers

  • Molecular and Cellular Biochemistry
  • Occupational Health and Safety.