Determination of L-Fucose in Glycoproteins. I. Effect of Nonfucose Moieties of Serum Glycoproteins

Abstract

The effect of galactose, mannose, and tryptophan on the determination of the methylpentose L-fucose in glycoproteins by the cysteine-sulfuric acid reaction is described. Under certain analytical conditions, protein-bound hexoses significantly contribute to the apparent fucose level. The true fucose level may be approximated under these same conditions by means of an empirically derived equation relating the concentration of serum protein-bound hexoses to the true fucose level. Fucose levels obtained with pathological and nonpathological sera by various methods are compared and specific conditions for the reliability of the statistics are defined and discussed.

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Document Details

Document Type
Technical Report
Publication Date
Apr 01, 1972
Accession Number
AD0745747

Entities

People

  • K. M. Hartley
  • P. Z. Sobocinski
  • W. J. Canterbury

Organizations

  • Armed Forces Radiobiology Research Institute

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  • Biomedical

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  • Absorption
  • Absorption Spectra
  • Biochemistry
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Fields of Study

  • Biology

Readers

  • Analytical Chemistry
  • Molecular and Cellular Biochemistry
  • Regression Analysis.