Development of Methods for Neurorrhaphy and the Treatments of Spinal Cord and Cauda Equina Injuries in Battle Casualties.
Abstract
A 400 gm-cm force exerted on the exposed feline spinal cord leads to its destruction by hemorrhage and edema approximately four hours after impact. One hour after trauma, simultaneous intravenous administration of Epsilon aminocaproic acid and methyl prednisolone sodium succinate appreciably protects the tissue of the spinal cord by minimizing hemorrhage and edema. At 24 hours, a spinal cord so treated compares favorably with an untreated control specimen removed 2 minutes after impact. It appears that therapy may possibly have gained three more hours of time after spinal cord contusion before instituting definitive surgical methods. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 01, 1972
- Accession Number
- AD0746988
Entities
People
- James B. Campbell
Organizations
- New York University