Kininases.

Abstract

Bradykinin is inactivated when any one of its eight peptide bonds is cleaved. The term kininase was coined when the structure of kinins was still unknown, although enzymes should obviously not be named after a single substrate. It indicates the existence of an enzyme capable of inactivating bradykinin. Kininases are widely distributed in nature. Their sources range from human blood to bacteria. The two enzymes discussed are kininase I (or carboxypeptidase N) and kininase II (or peptide dipeptide hydrolase).

Document Details

Document Type
Technical Report
Publication Date
Aug 25, 1972
Accession Number
AD0747639

Entities

People

  • E. G. Erdos
  • H. S. J. Yeh
  • K. Sorrells
  • R. Igic
  • T. Nakajima

Organizations

  • University of Oklahoma Health Sciences Center

Tags

DTIC Thesaurus Topics

  • Bacteria
  • Biomolecules
  • Chemical Compounds
  • Enzymes
  • Enzymes And Coenzymes
  • Hydrolases
  • Substrates

Fields of Study

  • Biology
  • Computer science

Readers

  • Molecular and Cellular Biochemistry