Detection of an Endotoxin-Like Substance during Human Plague Bacteremia

Abstract

The report describes a bioassay for detection of endotoxin activity in stored plasma. The procedure is based on the ability of actinomycin-D to enhance susceptibility of mice to endotoxin. Application of this method has permitted detection of an endotoxin-inlike substance in a patient with terminal plague bacteremia.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 1972
Accession Number
AD0747743

Entities

People

  • Richard I. Walker

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Animals
  • Bacteria
  • Bioassay
  • Biological Toxins
  • Cardiovascular Physiological Phenomena
  • Coinfection
  • Detection
  • Electrocardiography
  • Endotoxins
  • Fungi
  • Health
  • Health Services
  • Infection
  • Microbiology
  • New Hampshire
  • Public Health
  • Rodents

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  • Microbial Pathology