Selective Reductions via Hydrides.

Abstract

The syntheses, modifications, and chemistry of sodium borohydride and lithium aluminum hydride have been investigated. Research has made it possible to prepare a wide variety of alkyl substituted borohydrides, LiR3BH. These are the most powerful and highly stereoselective reducing agents now available to organic chemists. These have been used in the total synthesis of prostaglandins. Research has opened up a detailed exploration of chloroboranes. These derivatives react rapidly with olefins to produce dialkylboron chloride in excellent yield. (Author)

Document Details

Document Type
Technical Report
Publication Date
Oct 01, 1972
Accession Number
AD0750717

Entities

People

  • Herbert C. Brown

Organizations

  • Purdue Research Foundation

Tags

DTIC Thesaurus Topics

  • Aluminum
  • Aluminum Hydride
  • Borohydrides
  • Chemical Compounds
  • Chemical Synthesis
  • Chemistry
  • Chlorides
  • Hydrides
  • Prostaglandin
  • Reducing Agents

Fields of Study

  • Chemistry

Readers

  • Organic Chemistry