Case for Diagnosis

Abstract

A 13 year old male Barbary ape (Macaca sylvana) from the National Zoological Park, Washington, D. C., died after a one-day illness characterized by lethargy and prostration. Although two other Barbary apes had died of an apparently similar cause within several weeks of this time, there were no clinical signs in 23 other nonhuman primates housed in the same colony. At necropsy this animal was icteric, and there were widespread petechiae and ecchymoses of visceral organs. Spirochetes could be demonstrated with Warthin- Starry silver stain in both kidney and liver tissue. Although leptospires were not isolated from the tissue because of freezing prior to processing, they were isolated from the liver and kidneys of the other two Barbary apes that died. By utilizing cross-agglutimation reactions it was found that the isolates cross- reacted with antiserums for serotype icterohaemorrhagiae. The local environment and the sequence of morbidity in the colony of apes seemed to favor an exogenous source of infection, most likely wild rodents known to be in the area.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1972
Accession Number
AD0751352

Entities

People

  • F. M. Garner
  • Frank A. Voelker

Organizations

  • Armed Forces Institute of Pathology

Tags

DTIC Thesaurus Topics

  • Antibodies
  • Congestion
  • Contamination
  • Diseases And Disorders
  • Environment
  • Freezing
  • Hematologic Diseases
  • Immune Serums
  • Infection
  • Inoculation
  • Lymphocytes
  • Military Medicine
  • Morbidity
  • Neurobehavioral Manifestations
  • Sequences
  • Vascular Congestion
  • Wound Infections

Fields of Study

  • Biology
  • Medicine

Readers

  • Neurodegenerative Parkinson's Disease and Rickettsial Disease handbook, including the data level of dopamine, BC, neurons, and PD.
  • Toxicology/Environmental Toxicology
  • Virology (or Medical Virology).