Virological Studies in Dolphins.

Abstract

Serologic tests have disclosed that the blood of 'normal; dolphins contains antibodies to a number of viruses infectious for man. The hemagglutination test presented no problems, but the complement fixation test was complicated by an anticomplementary activity encountered in the sera of all dolphins. This activity could be removed by precipitating the serum at low ionicity. The supernatant in these precipitates still contained antibody activity as measured by both the complement fixation and hemagglutination tests. Following experimental infection with influenza A2 an increase an in specific antibodies was demonstrated. The earliest antibody was exclusively a macroglobulin, presumably a counterpart of 19S IgM of terrestrial mammals. With passage of time, there was the appearance of a 7S antibody, presumably of the IgG type. (Author)

Document Details

Document Type
Technical Report
Publication Date
Nov 01, 1972
Accession Number
AD0751688

Entities

People

  • Michael Sigel

Tags

DTIC Thesaurus Topics

  • Antibodies
  • Bacterial Infections And Mycoses
  • Diseases And Disorders
  • Hemagglutination Tests
  • Infection
  • Influenza
  • Microorganisms
  • Precipitates
  • Serodiagnosis
  • Viruses
  • Wound Infections

Fields of Study

  • Biology
  • Medicine

Readers

  • Systems Analysis and Design
  • Virology (or Medical Virology).